Reliability is not straightforward regarding transmission tunes. If you're running a lot of boost and the transmission starts to slip while engaged, which probably can be cured by a tune the opposite happens. A tune increases reliabilty, rather then decreasing it.
In general it's not always "tuning" in terms of going more aggressive. A lot of things can be tweaked to how the driver prefers them to be, but have nothing to do with reliability. Think about shift points. Some want shifts as early as possible, others want the opposite. Nothing good or bad about that, it's just personal liking. Or TCC slip. The stock calibration lets the transmission slip a lot with modulated TCC pressure. Personally i hate slip, so I configured the TCC to stay closed as long as possible. Less slip equals less wear in that case. On the other side, if someone wants the fastest shifts possible and likes torque punches on each shift (like a lot of the DCT transmissions do it in Sport Mode) it will of course wear out the clutch packs in the long run. All I can say is, that no OTS map we will be delivering will test the limits. We will do our best, to deliver safe and reliable tunes for everyday use.
I have lot's of BMW files and various Alpina calibrations here and investigated them thouroughly. Additionally my own car will have a few 1000 miles with the tune on it, when we will release in February. And of course, my car is the main development bitch, which has probably 100+ full throttle launches on it right now.